A model for the taxol (paclitaxel)/epoth
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Jeffrey D. Winkler; Paul H. Axelsen
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Article
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1996
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Elsevier Science
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English
⚖ 222 KB
Epothilone is a recently discovered compound that appears to bind at the same microtubule-binding site as the anticancer agent taxol. A model for the pharmacophore common to these structurally dissimilar compounds is presented.