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Mutants of Chinese hamster ovary cells with altered sensitivity to taxol and benzimidazole carbamates

โœ Scribed by WARR, J; FLANAGAN, D; ANDERSON, M


Book ID
122135095
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
366 KB
Volume
6
Category
Article
ISSN
0309-1651

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Taxol resistant mutants of Chinese hamst
โœ Radhey S. Gupta ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 706 KB

The effects of the microtubule inhibitor taxol on the growth and viability of Chinese hamster ovary (CHO) cells have been examined. Stable mutants which are between seven to 11-fold more resistant to taxol have been selected in a single step from ethyl methanesulfonate-mutagenized CHO cells. The two