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Mutant p53 mediates survival of breast cancer cells

✍ Scribed by Lim, L Y; Vidnovic, N; Ellisen, L W; Leong, C-O

Book ID
110000189
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
508 KB
Volume
101
Category
Article
ISSN
0007-0920

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P53 mediated regulation of metallothione
P53 mediated regulation of metallothionein transcription in breast cancer cells
✍ Elena A. Ostrakhovitch; Per-Erik Olsson; Jonas von Hofsten; M. George Cherian πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 364 KB

## Abstract Recent studies have shown that only breast cancer epithelial cells with intact p53 can induce metallothionein (MT) synthesis after exposure to metals. In this study, the potential role of p53 on regulation of MT was investigated. Results demonstrate that zinc and copper increased metal