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Mutagenicity of the phenolic microsomal metabolites of 3-nitrofluoranthene and 1-nitropyrene in strains of Salmonella typhimurium

✍ Scribed by Mary C. Consolo; Monika Anders; Paul C. Howard


Book ID
113193628
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
560 KB
Volume
210
Category
Article
ISSN
0027-5107

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The male rabbit liver microsomal cytochrome P450 metabolism of 1-nitropyrene and 3- nitrofluoranthene was investigated. In this study, we used inhibitory antibodies specific for rabbit P450 2C3 and determined that, in untreated male rabbit liver microsomes, the antibody inhibited approximately 75% o