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Mutagenicity of the human bladder carcinogen 4-aminobiphenyl to the bladder of Muta ™Mouse transgenic mice

✍ Scribed by K. Fletcher; H. Tinwell; J. Ashby

Book ID
114072305
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
65 KB
Volume
400
Category
Article
ISSN
0027-5107

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✍ Melissa S. Burger; Jennifer L. Torino; Santhanam Swaminathan 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 519 KB

The DNA damage induced by N-hydroxy-4-acetylaminobiphenyl (N-OH-AABP), the proximate carcinogenic metabolite of the human bladder carcinogen 4-aminobiphenyl (ABP), was examined in human transitional cell carcinoma (TCC) cells after exposure to the chemical in vitro. 32P-postlabeling analysis of TCC