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Mutagenic activation of urinary bladder carcinogens by CYP4B1 and the presence of CYP4B1 in bladder mucosa

✍ Scribed by Susumu Imaoka; Yukio Yoneda; Tsutomu Matsnda; Masakuni Degawa; Shoji Fukushima; Yoshihiko Funae


Book ID
119407352
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
809 KB
Volume
54
Category
Article
ISSN
0006-2952

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✍ Vladimir Mastyugin; Alexandre Mezentsev; Wen-Xiang Zhang; Silvia Ashkar; Michael πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 846 KB

## Abstract Hypoxic injury to the ocular surface provokes an inflammatory response that is mediated, in part, by corneal epithelial‐derived 12‐hydroxyeicosanoids. Recent studies indicate that a cytochrome P450 (CYP) monooxygenase, identified as CYP4B1, is involved in the production of these eicosan