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Mutagenicity of 7H-dibenzo[c,g]carbazole and its tissue specific derivatives in genetically engineered Chinese hamster V79 cell lines stably expressing cytochrome P450

✍ Scribed by Alena Gábelová; Timea Farkašová; Gabriela Bačová; Soňa Robichová

Book ID
117766929
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
105 KB
Volume
517
Category
Article
ISSN
1383-5718

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DNA adduct formation by 7H-dibenzo[c,g]carbazole and its tissue- and organ-specific derivatives in Chinese hamster V79 cell lines stably expressing cytochrome P450 enzymes
✍ Alena Gábelová; Blanka Binková; Zuzana Valovičová; Radim J. Šrám 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 249 KB 👁 1 views

## Abstract The cytochrome P4501A subfamily (CYP1A) is involved in the metabolic activation of __7H__‐dibenzo[__c,g__]carbazole (DBC) and its tissue‐ and organ‐specific derivatives, __N__‐methyldibenzo[__c,g__]carbazole (MeDBC)and 5,9‐dimethyldibenzo[__c,g__]carbazole (diMeDBC). In this study, we h