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Mutagenicity in Salmonella assays of cyclohexane epoxide derivatives

✍ Scribed by Frantz, S.W.; van den Eeckhout, E.; Sinsheimer, J.E.; Yoshihara, M.; Koreeda, M.


Book ID
122525564
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
425 KB
Volume
25
Category
Article
ISSN
0378-4274

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4,4'-Methylenedianiline and its derivatives were assayed for mutagenicity in the Salmonella/microsomal mutagenicity assay developed by Ames. A specificity to revert strain TA98 suggests a mechanism of frameshift mutagenesis. Liver microsomal preparations (S-9) from rats induced with phenobarbital we