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Mutagenicity evaluation of Schistosoma spp. extracts by the umu-test and V79/HGPRT gene mutation assay

✍ Scribed by Yoshio Osada; Takashi Kumagai; Kyoko Masuda; Tomoyuki Suzuki; Tamotsu Kanazawa


Book ID
119342500
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
114 KB
Volume
54
Category
Article
ISSN
1383-5769

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## Abstract The mutagenic potential of zinc pyrithione (Znpt) was evaluated __in vitro__ in the __Salmonella__/mammalian microsome plate incorporation mutagenicity (Ames) assay and the CHO/HGPRT gene mutation assay. The clastogenic potential of Znpt was evaluated __in vivo__ using the mouse micronu