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Cytotoxicity, genotoxicity and antimutagenicity of hexane extracts of Agaricus blazei determined in vitro by the comet assay and CHO/HGPRT gene mutation assay

✍ Scribed by Melissa Pereira Machado; Edson Rodrigues Filho; Ana Paula Terezan; Lúcia Regina Ribeiro; Mário Sérgio Mantovani


Book ID
116919250
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
130 KB
Volume
19
Category
Article
ISSN
0887-2333

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## Abstract The mutagenic potential of zinc pyrithione (Znpt) was evaluated __in vitro__ in the __Salmonella__/mammalian microsome plate incorporation mutagenicity (Ames) assay and the CHO/HGPRT gene mutation assay. The clastogenic potential of Znpt was evaluated __in vivo__ using the mouse micronu