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Mutagenic activation of 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole(Trp-P-1) and 3-amino-1-methyl-5H-pyrido(4,3-b)indole (Trp-P-2) by primary cultures of adult rat hepatocytes: Effect of Aroclor induction in vitro

✍ Scribed by F. Decloître; G. Hamon; M. Martin; V. Thybaud-Lambay

Book ID
119092688
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
721 KB
Volume
137
Category
Article
ISSN
0165-1218

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Synthesis of 3-amino-1-methyl-5H-pyrido[4,3-b]indole-1-14C (TRP-P-2)
✍ E. J. Reist; W. W. Bradford; G. R. Gordon; J. H. Peters 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 French ⚖ 191 KB 👁 1 views

## Abstract A practical 2‐step synthesis of 3‐amino‐1‐methyl‐5H‐pyrido[4,3‐b]indole‐1‐^14^C is described, starting from 2‐cyanomethyl indole and carbonyl‐labeled acetyl chloride.