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Mutagenesis in cultured mammalian cells: II. Induction of gene mutations in Chinese hamster cells

✍ Scribed by N.I. Shapiro; A.E. Khalizev; E.V. Luss; E.S. Manuilova; O.N. Petrova; N.B. Varshaver


Book ID
116036439
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
819 KB
Volume
16
Category
Article
ISSN
0027-5107

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The effect of ploidy on chemical mutagen
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## Abstract The frequency of mutations induced by ethyl methane sulfonate was compared in a pseudodiploid Chinese hamster cell strain and in a tetraploid substrain derived from it. The frequency of reverse mutations from glycine auxotrophy to glycine independence was similar in the two strains, as