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Mutagenecity of vinyl chloride, vinylidene chloride and chloroprene in V79 Chinese hamster cells

✍ Scribed by C. Drevon; T. Kuroki

Book ID
119092008
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
593 KB
Volume
67
Category
Article
ISSN
0165-1218

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Mutation induction in chinese hamster V7
Mutation induction in chinese hamster V79 cells by two vinyl chloride metabolites, chloroethylene oxide and 2-chloroacetaldehyde
✍ Eliezer Huberman; Helmut Bartsch; Leo Sachs 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 French ⚖ 421 KB

## Abstract Chloroethylene oxide and 2‐chloroacetaldehyde, two possibly carcinogenic metabolites of vinyl chloride in mammals, caused a dose‐dependent induction of 8‐azaguanine‐and ouabain‐resistant mutants in Chinese hamster V79 cells in vitro. Up to one‐hundredfold higher concentrations of 2‐chlo