Numerous in vivo studies have demonstrated that recombinant AAV-2 vectors (rAAV-2) can efficiently transduce many tissues and lead to stable gene expression 12. These encouraging results have led to a rapid development of clinical trials involving the use of rAAV-2 vectors 3. However, the obtainment
✦ LIBER ✦
Muta-Pro: Towards the definition of a mutation testing process
✍ Scribed by A. M. R. Vincenzi; A. S. Simão; M. E. Delamaro; J. C. Maldonado
- Publisher
- SciELO
- Year
- 2006
- Tongue
- English
- Weight
- 302 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0104-6500
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Advances in molecular biology and genetics have led to the identification of the breast/ovarian cancer susceptibility genes BRCA1 and BRCA2, along with tests to detect mutations in these genes. Although the appropriateness of BRCA1/2 genetic testing for children has been debated in the literature, l