𝔖 Bobbio Scriptorium
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Muscular atrophy: Activation of mitochondrial ATPase

✍ Scribed by Stephen R. Max

Book ID
118853863
Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
334 KB
Volume
52
Category
Article
ISSN
0006-291X

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## Abstract Mutations of the survival motor neuron (SMN) gene in spinal muscular atrophy (SMA) lead to anterior horn cell death. The cause is unknown, but motor neurons depend substantially on mitochondrial oxidative phosphorylation (OxPhos) for normal function. Therefore, mitochondrial parameters