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Muscle development in mdx mutant mice

โœ Scribed by Josette Dangain; Dr. Gerta Vrbova


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
756 KB
Volume
7
Category
Article
ISSN
0148-639X

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Inhibition of muscle degeneration by the tripeptide calpain inhibitor, leupeptin, was tested in vivo in a dystrophin-deficient mdx murine model. In a short-term control study, intramuscular administration of leupeptin for 30 days inhibited muscle degeneration as assessed by histologic analysis. Calp