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Muscarinic acetylcholine m1–m4 receptors overexpressed in neuroblastoma-glioma hybrid NG108-15 cells as a cholinergic model

✍ Scribed by H. Higashida; S. Yokoyama; N. Hoshi; M. Hashii; A. Egorova; Z.-G. Zhong


Book ID
114303743
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
221 KB
Volume
92
Category
Article
ISSN
0928-4257

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External application of bradykinin (BK) to mouse neuroblastoma x mouse fibroblast hybrid NL308 cells and mouse neuroblastoma x rat glioma hybrid NG108-15 cells produced a transient outward (hyperpolarizing) current. In NG108-15 cells, BK also induced an inward (depolarizing) current associated with