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Genotypic m3-Muscarinic Receptors Preferentially Inhibit M-currents in DNA-transfected NG108-15 Neuroblastoma × Glioma Hybrid Cells

✍ Scribed by J. Robbins; M. P. Caulfield; H. Higashida; D. A. Brown


Book ID
109016885
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
501 KB
Volume
3
Category
Article
ISSN
0953-816X

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Inhibition of the M current in NG108-15
✍ Sabine Schäfer; Philippe Béhé; Hans Meves 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 934 KB

The M current, IM, a voltage-dependent noninactivating K current, was recorded in NG108-15 neuroblastoma x glioma hybrid cells, using the whole-cell mode of the patch-clamp technique. We studied inhibition of the M current by bradykinin, phorbol dibutyrate (PDBu), an activator of protein kinase C (P