๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Murine strain differences in metabolism and bladder toxicity of cyclophosphamide

โœ Scribed by Lucy Fraiser; James P. Kehrer

Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
843 KB
Volume
75
Category
Article
ISSN
0300-483X

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Cellular target of cyclophosphamide toxi
Cellular target of cyclophosphamide toxicity in the murine liver: Role of glutathione and site of metabolic activation
โœ L D DeLeve ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 302 KB

in hepatocytes, and that SEC glutathione (GSH) plays a ma-Hepatic venoocclusive disease (HVOD) is caused by jor role in detoxification. 10,11 Furthermore, the evidence sugthe disruption of the microcirculation by an as-yet ungests that profound depletion of SEC GSH might be the comknown mechanism. P

Identification of genetic differences in
Identification of genetic differences in drug metabolism: Prediction of individual risk of toxicity or cancer
โœ Daniel W. Nebert ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 448 KB

differences exist in the regulation of at least some of the P450s (10). As the molecular mechanisms that underlie induction of human liver P45Os are characterized, it is likely that cell-free assays will be developed to screen drugs for induction properties. These two reports describe recombinant D