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Murine lupus in MRL/lpr mice lacking CD4 or CD8 T cells

✍ Scribed by Dow-Rhoon Koh; Alexandra Ho; Amin Rahemtulla; Wai-Ping Fung-Leung; Henrik Griesser; Tak-Wah Mak

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
525 KB
Volume
25
Category
Article
ISSN
0014-2980

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## Ipr T cells vaccinate against lupus in MRLllpr mice* MRLIMP-lprllpr mice are homozygous for the Ipr mutation that results in the accumulation of phenotypically abnormal cells (CD3+CD4+CDST) in all lymphoid issues. Although no major abnormalities in the T cell receptor repertoire expressed by su