✦ LIBER ✦

Multistage designs for phase II clinical trials: statistical issues in cancer research

✍ Scribed by Kramar, A; Potvin, D; Hill, C

Book ID: 109837311
Publisher: Nature Publishing Group
Year: 1996
Tongue: English
Weight: 892 KB
Volume: 74
Category: Article
ISSN: 0007-0920
DOI: 10.1038/bjc.1996.537

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Optimal three-stage designs for phase II

Optimal three-stage designs for phase II cancer clinical trials

✍ T. Timothy Chen 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 136 KB 👁 2 views

The objective of a phase II cancer clinical trial is to screen a treatment that can produce a similar or better response rate compared to the current treatment results. This screening is usually carried out in two stages as proposed by Simon. For ineffective treatment, the trial should terminate at

Practical issues in quality of life asse

Practical issues in quality of life assessment in multicentre trials conducted by the Swiss Group for Clinical Cancer Research

✍ Jürg Bernhard; Heidi Gusset; Christoph Hürny 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB 👁 2 views

Quality of life (QOL) assessment has become an integrated part in some advanced disease trials and to a lesser extent in early disease trials conducted by the Swiss Group for Clinical Cancer Research (SAKK). In general, the concept of QOL endpoints and the additional work of collecting these data is

Phase I/II study of the anti-oestrogen z

Phase I/II study of the anti-oestrogen zindoxifene (D16726) in the treatment of advanced breast cancer. A Cancer Research Campaign Phase I/II Clinical Trials Committee study

✍ Stein, RC; Dowsett, M; Cunningham, DC; Davenport, J; Ford, HT; Gazet, J-C; von A 📂 Article 📅 1990 🏛 Nature Publishing Group 🌐 English ⚖ 649 KB

Response of patients in phase II studies

Response of patients in phase II studies of chemotherapy in ovarian cancer: implications for patient treatment and the design of phase II trials

✍ Blackledge, G; Lawton, F; Redman, C; Kelly, K 📂 Article 📅 1989 🏛 Nature Publishing Group 🌐 English ⚖ 604 KB

Gemcitabine with or without continuous i

Gemcitabine with or without continuous infusion 5-FU in advanced pancreatic cancer: a randomised phase II trial of the Italian oncology group for clinical research (GOIRC)

✍ Di Costanzo, F; Carlini, P; Doni, L; Massidda, B; Mattioli, R; Iop, A; Barletta, 📂 Article 📅 2005 🏛 Nature Publishing Group 🌐 English ⚖ 97 KB

Phase II clinical trial ofcis-dichlorodi

Phase II clinical trial ofcis-dichlorodiammine platinum (cis-DDP) for antitumorigenic activity in previously untreated patients with metastatic breast cancer

✍ Krsto Kolarić; Anton Roth 📂 Article 📅 1983 🏛 Springer 🌐 English ⚖ 467 KB