[Multipoint Linkage Analysis Using Affected Relative Pairs and Partially Informative Markers]: Rejoinder
β Scribed by Jun Teng and David Siegmund
- Book ID
- 125771920
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 782 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0006-341X
- DOI
- 10.2307/2533657
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## Abstract Recently, Liang et al. ([2001b] Genet. Epidemiol. 21:105β122) proposed a conditional approach to assess linkage evidence on the target region by incorporating linkage information from an unlinked (reference) region using allele shared IBD (identityβbyβdecent) from affected sib pairs. Th
## Abstract In this paper, we proposed a multipoint method to assess evidence of linkage to one region by incorporating linkage evidence from another region. This approach uses affected sib pairs in which the number of alleles shared identical by descent (IBD) is the primary statistic. This general