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Approximation of the p-value in a multipoint linkage analysis using partially informative markers

โœ Scribed by B. Yakir


Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
478 KB
Volume
47
Category
Article
ISSN
0362-546X

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Multipoint linkage analysis of the short
โœ S. O'Rahilly; P. Patel; O. J. Lehmann; A. Tybjaerg-Hansen; J. Nerup; R. C. Turne ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 510 KB

Members of three families with maturity onset diabetes of youth (MODY) and seven with "common" type 2 diabetes were typed for six DNA markers (H-RAS, INS, HBBC, PTH, CALC1, CAT) on the short arm of chromosome 11. Using conventional pairwise linkage analysis, close linkage in the MODY families was ex