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Multiplicity in randomised trials I: endpoints and treatments

✍ Scribed by Kenneth F Schulz; David A Grimes

Book ID
117289419
Publisher
The Lancet
Year
2005
Tongue
English
Weight
239 KB
Volume
365
Category
Article
ISSN
0140-6736

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πŸ“œ SIMILAR VOLUMES

Multiplicity in randomised trials II: su
Multiplicity in randomised trials II: subgroup and interim analyses
✍ Kenneth F Schulz; David A Grimes πŸ“‚ Article πŸ“… 2005 πŸ› The Lancet 🌐 English βš– 185 KB

Subgroup analyses have specious appeal. They seem logical and intuitive-and even fun-to both investigators and readers. However, this insidious appeal causes important problems. Multiplicity and naivetΓ© combine to encourage interpretational missteps in trial conduct and reporting. The subgroup treat