Multiplex Single Strand Conformation Polymorphism Analysis by Capillary Electrophoresis with On-the-Fly Fluorescence Lifetime Detection
β Scribed by Snyder, Tara Morcone; McGown, Linda B.
- Book ID
- 115365267
- Publisher
- Society for Applied Spectroscopy
- Year
- 2005
- Tongue
- English
- Weight
- 88 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0003-7028
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## Single strand conformational polymorphism using capillary electrophoresis with two-dye laser-induced fluorescence detection Capillary electrophoresis (CE), using a replaceable polymer matrix and twodye laser-induced fluorescence has been applied to single strand conformational palymorphism (SSC
We investigated the effects of temperature and pH on single strand-conformation polymorphism (SSCP) analyzed by capillary electrophoresis (CE) using short-chain linear polyacrylamide as the sieving medium. Nine different mutations (in factor V, cystathionine b-synthase, and methylenetetrahydrofolate