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Automated DNA mutation analysis by single-strand conformation polymorphism using capillary electrophoresis with laser-induced fluorescence detection

✍ Scribed by Ming-Sun Liu; Sushma Rampal; David Hsiang; Fu-Tai A. Chen


Book ID
111640109
Publisher
Humana Press Inc
Year
2000
Tongue
English
Weight
118 KB
Volume
15
Category
Article
ISSN
1073-6085

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Capillary array electrophoresis (CAE) is a novel technique, which allows for high throughput analysis of DNA fragments. When screening for mutations in whole populations or large patient groups it is necessary to have robust and well-characterized setups for high throughput analysis. For large-scale