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Multiplex fluorescence in situ hybridization in identifying chromosome involvement of complex karyotypes in de novo myelodysplastic syndromes and acute myeloid leukemia

✍ Scribed by W. XU; J.-Y. LI; Q. LIU; Y. ZHU; J.-L. PAN; H.-R. QIU; Y.-Q. XUE


Book ID
111415146
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
564 KB
Volume
32
Category
Article
ISSN
1751-5521

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## Abstract Double minute chromosomes (dmin) are small chromatin bodies consisting of genes amplified in an extrachromosomal location. dmins are uncommon in hematologic malignancies; they are seen primarily in acute myeloid leukemia, with amplification of the __MYC__ oncogene or, less frequently, t