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Multiple sulfa compounds: High-pressure liquid chromatographie assay and mobile phase correlation

✍ Scribed by E. C. Jennings; W. C. Landgraf

Publisher: John Wiley and Sons
Year: 1977
Tongue: English
Weight: 266 KB
Volume: 66
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600661238

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✦ Synopsis

A mixture of sulfacetamide, sulfathiazole, and sulfabenzamide was used to develop a rapid high-pressure liquid chromatographic assay. In addition, this study provided a means to develop concepts relating solvent molar polarization parameters and retention times. A linear correlation between molar polarization and retention time was observed and will permit reasonably rapid predictions about the dependent variable.

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