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Multiple sclerosis and optic neuritis: CCR5 and CXCR3 expressing T cells are augmented in blood and cerebrospinal fluid

✍ Scribed by Natalia Teleshova; Mikhail Pashenkov; Yu-Min Huang; Mats Söderström; Pia Kivisäkk; Vasilios Kostulas; Mats Haglund; Hans Link


Publisher
Springer
Year
2002
Tongue
English
Weight
494 KB
Volume
249
Category
Article
ISSN
0340-5354

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To better characterize the inflammatory response that occurs in the nervous system in multiple sclerosis (MS), T-cell receptor (TCR) gene expression was quantified from cerebrospinal fluid (CSF) cells of 21 patients with active disease. Unstimulated CSF cells expressed each of 22 different TCR beta