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Multiple sclerosis: a white matter disease with associated gray matter damage

✍ Scribed by Massimo Filippi

Book ID: 119465344
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 36 KB
Volume: 185
Category: Article
ISSN: 0022-510X
DOI: 10.1016/s0022-510x(01)00476-2

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## Abstract Oxidative stress has been implicated in the pathophysiology of multiple sclerosis (MS). Increased levels of reactive oxygen species (ROS) derived from infiltrating macrophages and microglial cells have been shown to reduce the levels of endogenous antioxidants and to cause the oxidation