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MRI quantification of gray and white matter damage in patients with early–onset multiple sclerosis

✍ Scribed by P. Tortorella; M. A. Rocca; D. M. Mezzapesa; A. Ghezzi; L. Lamantia; G. Comi; M. Filippi


Publisher
Springer
Year
2006
Tongue
English
Weight
238 KB
Volume
253
Category
Article
ISSN
0340-5354

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## Abstract Oxidative stress has been implicated in the pathophysiology of multiple sclerosis (MS). Increased levels of reactive oxygen species (ROS) derived from infiltrating macrophages and microglial cells have been shown to reduce the levels of endogenous antioxidants and to cause the oxidation