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Multiple regions of α-synuclein are associated with Parkinson's disease

✍ Scribed by Jakob C. Mueller; Julia Fuchs; Anne Hofer; Alexander Zimprich; Peter Lichtner; Thomas Illig; Daniela Berg; Ullrich Wüllner; Thomas Meitinger; Thomas Gasser

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
178 KB
Volume
57
Category
Article
ISSN
0364-5134

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✍ Matt Farrer; Jennifer Kachergus; Lysia Forno; Sarah Lincoln; Deng-Shun Wang; Mar 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 211 KB

## Abstract Genomic triplication of the α‐synuclein gene recently has been associated with familial Parkinson's disease in the Spellman–Muenter kindred. Here, we present an independent family, of Swedish‐American descent, with hereditary early‐onset parkinsonism with dementia due to α‐synuclein tri