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Multiple recurrence of trisomy 21 Down syndrome

✍ Scribed by Kim Gjerum Nielsen; Hanne Poulsen; Margareta Mikkelsen; Elke Steuber


Publisher
Springer
Year
1988
Tongue
English
Weight
397 KB
Volume
78
Category
Article
ISSN
0340-6717

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Trisomy 21 Down syndrome
✍ Irene A. Uchida; C. P. Freeman πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 984 KB

In a series of 374 families with Down syndrome progeny, structural chromosome rearrangements were detected in the parents of six children with regular trisomy. The aberrations were reciprocal translocations and inversions. In all three informative families, the parent who transmitted the extra chrom

Trisomy 21 Down syndrome
✍ Irene A. Uchida; Viola C. P. Freeman πŸ“‚ Article πŸ“… 1985 πŸ› Springer 🌐 English βš– 311 KB

The lymphocyte chromosomes of trisomy 21 Down syndrome patients and their parents in a random series of 374 families were analyzed, the objective being the identification of parental mosaicism. The numbers of parents in whom at least two trisomy 21 cells were detected were seven mothers and three fa