It has been proposed that multiple quantum filtered (MQF) =Na NMR spectroscopy may distinguish between sodium in the intra-and extracellular spaces, in uiuo, and without the requirement for toxic shift reagents. We have investigated the origin of such signals in perfused rat hearts, using shift reag
Multiple-quantum-filtered 23Na NMR spectroscopy in model systems
β Scribed by Geoffrey S Payne; Peter Styles
- Publisher
- Elsevier Science
- Year
- 1991
- Weight
- 803 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0022-2364
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Triple quantum (TQ)-filtered 23Na NMR spectroscopy and the shift reagent, TmDOTP5-, have been used to evaluate the contributions of intra- (Na+i) and extracellular (Na+e) sodium to the TQ-filtered signal in the rat liver, in situ. Na+e contributed significantly to the total TQ-filtered signal in liv
## Abstract We investigated the contribution of extracellular Na^+^ to the multipleβquantum filtered ^23^Na NMR signal of perfused rat hearts to determine if the presence of shift reagent Dy(PPP__i__)~2~ and inorganic phosphate were somehow responsible for the generation of extracellular multiple q