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Multiple mitochondrial DNA deletions in an elderly human individual

✍ Scribed by Chunfang Zhang; Alessandra Baumer; Ronald J. Maxwell; Anthony W. Linnane; Phillip Nagley

Book ID
115926015
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
526 KB
Volume
297
Category
Article
ISSN
0014-5793

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## Abstract We report a patient with an autosomal dominant chronic progressive external ophthalmoplegia phenotype associated with multiple mtDNA deletions in muscle from a family in which linkage analysis excluded mutations in DNA polymerase Ξ³ (POLG), adenine nucleotide translocase (ANT‐1) or C10or