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Multiple mechanisms of estrogen receptor gene repression contribute to ER-negative breast cancer

✍ Scribed by Parl, F F


Book ID
110075280
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
53 KB
Volume
3
Category
Article
ISSN
1470-269X

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Estrogen receptor (ER) content is the most useful parameter for predicting hormone response therapy in breast cancer. Assays available for detecting ER in breast tumor cytosol are ligand-binding assay (LBA), which detects both ER␣ and ER␀, and the enzymatic immunoassay (EIA), in which monoclonal ant