✦ LIBER ✦

Multiple mechanisms are responsible for the alteration in the expression of HLA class I antigens in melanoma

✍ Scribed by Francisco Ruiz-Cabello; Catia Traversari; Federico Garrido

Publisher: John Wiley and Sons
Year: 2003
Tongue: French
Weight: 43 KB
Volume: 105
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.11076

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Molecular abnormalities in the expressio

Molecular abnormalities in the expression of HLA class-I antigens by melanoma cells

✍ Zhigang Wang; Yan Cao; Claudio D'Urso; Alan N. Houghton; Soldano Ferrone 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 377 KB 👁 1 views

Expression of HLA class I molecules and

Expression of HLA class I molecules and the transporter associated with antigen processing in hepatocellular carcinoma

✍ K Kurokohchi; M Carrington; D L Mann; T B Simonis; M A Alexander-Miller; S M Fei 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 268 KB 👁 1 views

caused by posttranscriptional events or failure to trans-The expression of the HLA class I molecules on the port and load peptides necessary for HLA expression. cell surface was investigated in hepatocellular carci-The selective loss of HLA-B and -C, but not -A, molecules noma (HCC) cell lines using

Simple elisa method for the evaluation o

Simple elisa method for the evaluation of soluble hla class i antigens in human serum

✍ Sergio Comuzio; Alessandro Orlandini; Franco Grillo; Dr. Francesco Puppo; Rosari 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 494 KB 👁 1 views

A simple sandwich ELISA method has been developed for the quantification of soluble HLA class I antigens (s-HLA) in human serum. The assay utilizes the monoclonal antibody Q6164, directed to a monomorphic determinant of the HLA a-chain, to capture the antigen and the biotinylated NAMB1 monoclonal an

IL-12 directly up-regulates the expressi

IL-12 directly up-regulates the expression of HLA class I, HLA class II and ICAM-1 on human melanoma cells: a mechanism for its antitumor activity?

✍ Feng Yun Yue; Ralf Geertsen; Silvio Hemmi; Günter Burg; Jovan Pavlovic; Elisabet 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB 👁 3 views

Coordinated downregulation of the antige

Coordinated downregulation of the antigen presentation machinery and HLA class I/β2-microglobulin complex is responsible for HLA-ABC loss in bladder cancer

✍ Jose María Romero; Pilar Jiménez; Teresa Cabrera; José Manuel Cózar; Susana Pedr 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 327 KB 👁 1 views

Downregulation of MHC class I expression is a widespread phenomenon used by tumor cells to escape antitumor T-cell-mediated immune responses. These alterations may play a role in the clinical course of the disease. The aim of our study was to investigate the molecular mechanism underlying the absenc

Favorable outcome in clinically stage II

Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T-lymphocytes and preserved MHC class I antigen expression

✍ Inge S. van Houdt; Berbel J.R. Sluijter; Laura M. Moesbergen; Wim M. Vos; Tanja 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 296 KB 👁 1 views

## Abstract In this study we investigated whether the presence of specific populations of tumor infiltrating lymphocytes (TILs) in diagnostic primary melanoma biopsies are related to outcome in clinically stage II melanoma patients. Moreover, we investigated whether the presence of TILs correlates