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Multiple karyotypic rearrangements, including t(X;18)(p11;q11), in a fibrosarcoma

✍ Scribed by Nils Mandahl; Sverre Heim; Kristina Arheden; Anders Rydholm; Helena Willén; Felix Mitelman


Book ID
119103926
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
636 KB
Volume
30
Category
Article
ISSN
0165-4608

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A synovial sarcoma with t(x;18)(p11;q11)
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## Abstract The first case of synovial sarcoma in a patient with Turner's syndrome (45,X) is reported. Cytogenetic analysis of the tumor cells showed that the only X chromosome was involved in the t(X;18)(p11;q11) characteristic of synovial sarcoma.

Masked t(X;18)(p11;q11) in a biphasic sy
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The initial cytogenetic analysis of a biphasic synovial sarcoma showed an apparently normal karyotype. After FISH using chromosome X-and 18-specific probes and RT-PCR using SYT-and SSX-specific primer sets, a cryptic synovial sarcomaassociated t(X;18)(p11;q11) could be revealed. The ''masked'' natur