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Multiple endocrine neoplasia type 1

✍ Scribed by B. Skogseid


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
56 KB
Volume
90
Category
Article
ISSN
0007-1323

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## Abstract ## Background Surgery in patients with multiple endocrine neoplasia type 1 (MEN1)-associated primary hyperparathyroidism (pHPT) is difficult as the condition it is caused by asymmetrical multiple gland hyperplasia. It is uncertain which operative procedure provides the best outcome wit

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## Background: Enteropancreatic malignancy is an important cause of morbidity and mortality associated with multiple endocrine neoplasia type 1 (men 1). however, the risk factors and mechanisms of the tumorigenesis of this malignancy are poorly understood. ## Methods: The authors conducted a retr

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Multiple endocrine neoplasia type 1 (MEN 1) is a familial cancer syndrome characterized by parathyroid hyperplasia, pituitary adenomas, and neuroendocrine tumors of the pancreas and duodenum. In 1997, the MEN1 tumor suppressor gene was identified, and numerous germline mutations have been reported t