✦ LIBER ✦

Multiple common fragile sites are expressed in the genome of the laboratory rat

✍ Scribed by T. J. Robinson; F. F. B. Elder

Publisher: Springer
Year: 1987
Tongue: English
Weight: 830 KB
Volume: 96
Category: Article
ISSN: 0009-5915
DOI: 10.1007/bf00285882

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The relationship between genetic suscept

The relationship between genetic susceptibility to head and neck cancer with the expression of common fragile sites

✍ Ünal Egeli; Lütfi Özkan; Berrin Tunca; Sibel Kahraman; Gülşah Çeçener; Emel Ergü 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB 👁 2 views

Neither age nor sex influence the expres

Neither age nor sex influence the expression of folate sensitive common fragile sites on human chromosomes

✍ Dominique F. C. M. Smeets; Gerard Merkx 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 254 KB

The expression of folate sensitive common fragile sites was investigated in 82 normal healthy males and females of various ages. In 100 studied metaphases of each of these controls, between 0 and 56 lesions were detected (mean 18.3 +/- 10.3 SD). No significant difference was found between the mean n

Increased expression of aphidicolin-indu

Increased expression of aphidicolin-induced common fragile sites in Tourette syndrome: The key to understand the genetics of comorbid phenotypes?

✍ Gericke, George S.; Simonic, Ingrid; Cloete, Elma; Becker, Piet J. 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 66 KB 👁 2 views

In a comparison of 80 common aphidicolin-induced fragile sites (FS) between 26 DSM-IV Tourette syndrome (TS) and 24 control individuals, the mean of the summed break frequencies following mild aphidicolin pretreatment was significantly higher in TS individuals than in controls (P < 0.001). Other bre

The effect of 1-β-d-arabinofuranosyl-cyt

The effect of 1-β-d-arabinofuranosyl-cytosine on the expression of the common fragile site at 3p14

✍ Xinzhi Li; Zu-an Yan; Xianting Zhou 📂 Article 📅 1986 🏛 Springer 🌐 English ⚖ 269 KB

Recurrent genomic rearrangements are not

Recurrent genomic rearrangements are not at the fragile sites on chromosomes 3 and 5 in human renal cell carcinomas

✍ G. Kovacs; P. Brusa 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 238 KB

It has been suggested that fragile sites on human chromosomes predispose to specific rearrangements seen in cancer. Renal cell carcinoma is characterised by recurrent aberrations of chromosome 3p and frequent rearrangements of chromosome 5q. To investigate whether there might be an association betwe

Variation in the expression of aphidicol

Variation in the expression of aphidicolin-induced fragile sites in human lymphocyte cultures

✍ Ann P. Craig-Holmes; Louise C. Strong; Angela Goodacre; Sen Pathak 📂 Article 📅 1987 🏛 Springer 🌐 English ⚖ 403 KB

A correlation between specific fragile sites and cancer breakpoints has been suggested raising the question of fragile site expression as a predisposing factor in the occurrence of cancer in some persons. Before addressing the question of increased fragility among patients at high risk for cancer, w