The effect of 1-β-d-arabinofuranosyl-cytosine on the expression of the common fragile site at 3p14
✍ Scribed by Xinzhi Li; Zu-an Yan; Xianting Zhou
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 269 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0340-6717
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## Abstract The cytotoxic effect of 1‐β‐D‐arabinofuranosyl cytosine (araC) depends on the intracellular phosphorylation into its active compound araCTP, on the degree of degradation of araCTP and on the incorporation of araCTP into DNA. Deoxycytidine triphosphate (dCTP) inhibits the phosphorylation
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