Multimodality therapy for patients with clinical Stage I and II malignant mixed Müllerian tumors of the uterus

✍ Scribed by Tom P. Manolitsas; Gerard V. Wain; Katherine E. Williams; Michael Freidlander; Neville F. Hacker

• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: English
• Weight: 84 KB
• Volume: 91
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(20010415)91:8<1437::aid-cncr1150>3.0.co;2-p

✦ Synopsis

BACKGROUND.

The role of adjuvant therapy in the management of patients with malignant mixed Mu ¨llerian tumors (MMMT) of the uterus has not been defined.

The outcome of planned multimodality therapy for patients with apparent early stage disease was assessed.

METHODS. A pilot study was performed on 38 patients with clinical Stage I or II

MMMTs of the uterus who were offered treatment according to a standard protocol. The protocol consisted of removal of the uterus, fallopian tubes, and ovaries and surgical staging followed by tailored radiation therapy and chemotherapy, consisting of cisplatin and epirubicin.