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Multifunctional substances — Determination of pKa-values by various methods

✍ Scribed by N. Sistovaris; Y. Hamachi; T. Kuriki

Book ID
112290776
Publisher
Springer
Year
1991
Tongue
English
Weight
369 KB
Volume
340
Category
Article
ISSN
1618-2650

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The acid-base behaviour of four benzodiazepines sparingly soluble in water (diazepam, medazepam, chlordiazepoxide and prazepam) was studied by potentiometric and spectrophotometric titrimetry in water. A method was devised to obtain the pK, values of these substances by potentiometric titrimetry in