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Multifunctional proteins revealed by overlapping clustering in protein interaction network

✍ Scribed by Becker, E.; Robisson, B.; Chapple, C. E.; Guenoche, A.; Brun, C.

Book ID
124154895
Publisher
Oxford University Press
Year
2011
Tongue
English
Weight
350 KB
Volume
28
Category
Article
ISSN
1367-4803

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In this paper, we study spectral clustering for detecting protein complexes in PPI (protein-protein interaction) networks, focusing on two open issues: (i) constructing similarity graphs; and (ii) determining the number of clusters. First, we study four similarity graphs to construct graph Laplacian