## Abstract Adefovir dipivoxil has been used alone or together with lamivudine to suppress lamivudineโresistant hepatitis B virus (HBV). However, the dynamics of HBV populations under different selection pressures and their impact on treatment outcome are poorly understood. Pyrosequencingยฎ was appl
Multidrug-resistant hepatitis B virus resulting from sequential monotherapy with lamivudine, adefovir, and entecavir: Clonal evolution during lamivudine plus adefovir therapy
โ Scribed by Kim, Soon Sun; Cho, Sung Won; Kim, Soo-Ok; Hong, Sun Pyo; Cheong, Jae Youn
- Book ID
- 118763103
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 479 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0146-6615
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## Abstract There is little clinical information on the management of hepatitis B virus (HBV) that is resistant to multiple drugs including entecavir (ETV). The present retrospective cohort study assessed the antiviral efficacy of ETV/adefovir dipivoxil (ADV) combination therapy for ETVโresistant H
## Abstract No study has reported on the comparative effect of adefovir (ADV) addโon lamivudine (LAM) versus switching to entecavir (ETV) in LAMโresistant patients with chronic hepatitis B. From October 2007 to September 2008, 92 consecutive LAMโresistant patients were enrolled (47 LAMโ+โADV and 45