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Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules

✍ Scribed by Frans G.M. Russel; Jan B. Koenderink; Rosalinde Masereeuw


Book ID
116918790
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
844 KB
Volume
29
Category
Article
ISSN
0165-6147

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## Abstract Several types of peripheral blood cells express ABC transporters. ABCC4 (MRP4) and ABCC5 (MRP5) localize to different cellular sites and fulfill lineage‐specific functions such as mediator storage in platelets' dense granules. All mature blood cells originate from the same precursor and