Effects of new 4-aryl-1,4-dihydropyridin
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Xiao-fei Zhou; Robert A. Coburn; Marilyn E. Morris
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Article
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2005
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John Wiley and Sons
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English
โ 164 KB
The purpose of this study is to evaluate the effects of newly synthesized 4aryl-1,4-dihydropyridine and pyridines on drug efflux mediated by multidrug resistanceassociated protein 1 (MRP1, ABCC1). These compounds were designed to maximize inhibition of P-glycoprotein and minimize calcium channel bin