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Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4

โœ Scribed by A A K El-Sheikh; J J M W Van Den Heuvel; J B Koenderink; F G M Russel


Book ID
109839151
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
201 KB
Volume
155
Category
Article
ISSN
0007-1188

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Effects of new 4-aryl-1,4-dihydropyridin
โœ Xiao-fei Zhou; Robert A. Coburn; Marilyn E. Morris ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 164 KB

The purpose of this study is to evaluate the effects of newly synthesized 4aryl-1,4-dihydropyridine and pyridines on drug efflux mediated by multidrug resistanceassociated protein 1 (MRP1, ABCC1). These compounds were designed to maximize inhibition of P-glycoprotein and minimize calcium channel bin