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Multicomponent Reactions with 1,3-Dicarbonyl Derivatives: Applications to the Synthesis of Polyfunctionalized Heterocycles

✍ Scribed by Thierry Constantieux; Jean Rodriguez


Publisher
John Wiley and Sons
Year
2007
Weight
18 KB
Volume
38
Category
Article
ISSN
0931-7597

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## Abstract magnified image The reaction of 2,3‐butanedione, ethyl pyruvate, and phenylglyoxal with β‐nitrostyrene and L‐proline in isopropanol at room temperature gives substituted pyrrolizidines, as a result of one‐pot three component reaction. On the contrary, a spiropyrrolizidine is formed fro