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Multicomponent complexes involved in kinetoplastid RNA editing

✍ Scribed by H.U. Göringer; J. Köller; H.H. Shu


Book ID
116110398
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
429 KB
Volume
11
Category
Article
ISSN
0169-4758

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Kinetoplastid RNA editing: complexes and
✍ Kenneth Stuart; Thomas E Allen; Moffett L Kable; Sobomabo Lawson 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 797 KB

RNA editing in kinetoplastids involves post-transcriptional insertion and deletion of uridylates (Us) to produce mature mitochondrial mRNAs with sequences specified by trans acting small guide RNAs. In vitro studies indicate the reaction pathway involves endonucleolytic cleavage of the precursor mRN