Multicolor fluorescence in situ hybridization with peptide nucleic acid probes for enumeration of specific chromosomes in human cells
โ Scribed by Krishan L. Taneja; Elizabeth A. Chavez; James Coull; Peter M. Lansdorp
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 341 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1045-2257
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Conventional Xand Y-chromatin and fluorescent in situ hybridization (FISH) analysis based on Xand Y-chromosome specific probes were conducted from buccal smear, on 15 normal males, 15 normal females, and 9 cases suspected of sex chromosome anomalies. The proportion of Xand Y-chromatin in normal fema
Change inchromosome number, numerical aneuploidy, has been consistently linked with cancer development. Since 90% of cancers arise in epithelial tissues, techniques that measure aneuploidy in these tissues would be very useful. Here we describe methods of optimization and suggest use of fluorescent